In many cases the cause for this is unknown, but may relate to genetic, autoimmune, or environmental (i.e. cancer treatment) factors.
Although less likely, spontaneous pregnancy is still possible, so these women should use contraception if they do not wish to become pregnant. They will also need careful hormonal supplementation to promote good bone health.
Treatment options for those wanting to conceive are limited, unfortunately. Typically, the use of a donated egg from a young healthy woman can be very successful, but adoption is also a viable solution.
